41368401.der.pdf
Metadata
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Added by Madison Feshuk on Apr 25, 2022 | |
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Extracted by http://clowder:9000/api/extractors/ncsa.file.digest on Apr 21, 2022 |
- filename: 41368401.der.pdf
- MRIDs: 41368401
- CHEMICAL_SUBSTANCE_NAME: Diethyl toluamide
- CHEMICAL_CASRN: 134-62-3
- CHEMICAL_PC_CODE: 080301
- STUDY_CITATION: Schardein, J. (1990) Neurotoxicity Evaluation in Rats following Multigeneration Exposure to Deet: Lab Project ID: 555-015. Un- blished study prepared by International Research and Develop- ment Corp. 238 p.
- STUDY_YEAR: 1990.0
- EXECUTIVE_SUMMARY: DEET: The sole neurotoxicologically significant effect was seen in high dose rats as an increase in motor activity at the beginning of the session. Body weight decreases of 10% and 15 %, respectively, were seen in rats during all periods measured at the two highest doses. LOAEL: Increased motor activity at 5,000 ppm (roughly 225 mg/kg); LOAEL: 2,000 ppm (roughly 90 mg/kg). The study is considered of acceptable quality [taken from the cover memo]. This is a valid and well conducted study. [There is no guideline requirement for this type of study.]
- STUDY_TYPE: Neurotoxicity
- GUIDELINE_COMMENT: NA [None]
- ADMIN_ROUTE: Oral
- DOSE_PERIOD: Treatment Duration: 2 Generations; special study
- txr: 9829.0
- memoDate: 1992-11-18
- UpdateDate: 2018-10-23
- Comments: Replaced with file with only DER that was already cleared
Extracted by
http://clowder:9000/api/extractors/ncsa.file.digest
on Apr 21, 2022
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| Type: | application/pdf |
| File size: | 407.1 kB |
| Uploaded on: | Apr 21, 2022 12:47:39 |
| Uploaded as: | 41368401.der.pdf |
| Uploaded by: | Madison Feshuk |
| Access: | Public |
| Status: | PROCESSED |
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| Views: | 10 |
| Last viewed: | Sep 10, 2025 05:17:04 |
| Downloads: | 59 |
| Last downloaded: | May 05, 2025 08:01:33 |
License
| Type: | blank |
| Holder: | blank |