All ToxCast materials associated with the invitrodb v4.1 release (September 2023), including the MySQL database, release notes, summary files, assay information and concentration response plots, are available here.
The Space team has made the following datasets and collections publicly available.
You must be a logged-in member of the Space to access all the datasets and collections.
This includes a zip file of summary files with descriptions available in README. Corrections: -mc6 method descriptions were missing in method list output file (see 11OCT2023 file) -"CytoPt" files referenced as being included in zip within Summary README had been renamed as "cytotox" files (README corrected 8JAN2024) -Uploaded annotations, gene mappings, and cytotox files so they can be linked outside of zip file -Uploaded v4.1 tcplVarMat output (variable matrices of hitcall and ac50s)
This .html output from Rmarkdown that describes the update of invitrodb between versions 3.5 and 4.1. Invitrodb version 4.1 represents the first full release of the ToxCast database in a new schema designed to accommodate the R package dependency, tcplFit2, which is used in curve-fitting and hit-calling of multi-concentration response data. This invitrodb schema was beta-tested with our research release of invitrodb v4.0 to accompany the manuscript, “The ToxCast Pipeline: Updates to Curve-Fitting Approaches and Database Structure” and release of tcpl v3.0.1.